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September 20, 2016     The Kalona News
New Cystic Fibrosis Treatment Delivers Antifungal Drugs to Lungs
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September 20, 2016
 

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'next' : 'previous'; __tnt. return true; }); } }, function(){ __tnt. });var bPrevNextScroll = false; $(window).on('scroll mousewheel', function(){ if( !bPrevNextScroll && $('.asset-body').length > 0 && !$('body').hasClass('trigger-disabled') && !__tnt.elementOnScreen('#asset-photo-carousel') ){ bPrevNextScroll = true; var sNextTrigger = 'trigger-next'; setTimeout(function(){ if( __tnt.elementOnScreen('.asset-body', 250) ){ $('body'). } else { $('body'). } bPrevNextScroll = false; }, 200); } });$(window).on("load resize", function(){ var sCondTrigger = 'trigger-condensed'; if( window.innerWidth > 991 && window.innerWidth < 1296 ){ var oWindow = $(window), iLeft = oWindow.scrollLeft(), oOffset = $("#main-page-container").offset(), iDistance = (oOffset.left - iLeft); if( iDistance < 55 ){ $('body'). } else { $('body'). } } else { $('body'). } }); }); advertorial New Cystic Fibrosis Treatment Delivers Antifungal Drugs to Lungs Updated 13 hrs ago 0 New treatment offers hope to cystic fibrosis patients with fungal infections in their lungs. jQuery(document).ready(function($){ var gallery_ad_ab6f86f0_fc29_5ea5_9ec6_7ddd8571e20f = false; var gallery_changed_ab6f86f0_fc29_5ea5_9ec6_7ddd8571e20f = false; $('#gallery-items-ab6f86f0-fc29-5ea5-9ec6-7ddd8571e20f').owlCarousel({ items: 1, autoHeight: true, lazyLoad: true, loop: false, navRewind: true, responsiveRefreshRate: 500, dots : false, onChanged: function(){ try { var bOnlyDFP = false, bIsOAS = false; if( typeof __tnt.ads.dfp != 'undefined' ){ googletag.cmd.push(function(){ googletag.pubads(). googletag.pubads(). });} /* reloadByIds will return false/0 if the ad slot called for hasn't actually been loaded to the page. */ if( typeof __tnt.ads.oas != 'undefined' ) bIsOAS = !!__tnt.ads.oas. if( !bOnlyDFP && !bIsOAS && typeof TNCMS.AdManager != 'undefined' ){ TNCMS.AdManager.} } catch(e) { __tnt. } }, onTranslated:function(){ __tnt.trackEvent($('#gallery-items-ab6f86f0-fc29-5ea5-9ec6-7ddd8571e20f .photo-container').eq(this._current).data('track-object')); } }); var photo_carousel_ab6f86f0_fc29_5ea5_9ec6_7ddd8571e20f = $('#gallery-items-ab6f86f0-fc29-5ea5-9ec6-7ddd8571e20f'). $('#carousel-ab6f86f0-fc29-5ea5-9ec6-7ddd8571e20f .photo-carousel-control.left').on(__tnt.client.clickEvent, function(e){ photo_carousel_ab6f86f0_fc29_5ea5_9ec6_7ddd8571e20f. }); $('#carousel-ab6f86f0-fc29-5ea5-9ec6-7ddd8571e20f .photo-carousel-control.right').on(__tnt.client.clickEvent, function(e){ photo_carousel_ab6f86f0_fc29_5ea5_9ec6_7ddd8571e20f. });}); (NewsUSA) - Up to half of all cystic fibrosis patients have fungal infections in their lungs caused by a spore-forming mold named Aspergillus fumigatus. Many of those patients, particularly children and young adults, will develop an allergic reaction to the fungus, Bronchopulmonary Aspergillosis (ABPA), according to the Cystic Fibrosis Foundation. Coughing, wheezing and other symptoms can be severe.Current treatments are oral drugs, including itraconazole. The problem is that high doses are needed to get enough of the drug to the lungs. That causes severe side effects that must be managed and monitored -- including liver toxicity. A more promising strategy is to deliver the itraconazole directly to the lungs by breathing it in. That's the approach taken by Lexington, Mass-based pharmaceutical company Pulmatrix, Inc. (NASDAQ: PULM). Pulmatrix's innovation was creating small, dense particles that can be easily inhaled, and combining them with drugs such as itraconazole."We've urgently needed a way to deliver antifungal drugs directly to the lungs," says Stanford University cystic fibrosis expert That's why the U.S. Food & Drug Administration has granted the company's request for orphan drug status for PUR1900, explaining that the designation "is based on a plausible hypothesis that [the] drug may be clinically superior to the same drug that is already approved." While PUR1900 has the potential to improve the lives of cystic fibrosis patients, especially children and young adults, it also could bring significant revenues for Pulmatrix. The estimated cystic fibrosis market alone is tens of thousands of patients a year, and the drug could also find much larger markets treating millions of other pulmonary fungal infections and other immunocompromised patients, making Pulmatrix a strong investment opportunity.For more information on PUR1900, go to https://www.youtube.com/watch?v=t8RgU8YUtjo. window._taboola = window._taboola || []; _taboola. !function (e, f, u) { e.async = 1; e.src = u; f.parentNode. }(document.createElement('script'), document.getElementsByTagName('script')[0], '//cdn.taboola.com/libtrc/townnews-network/loader.js'); window._taboola = window._taboola || []; _taboola. window._taboola = window._taboola || []; _taboola. × Post a comment Emoticons [smile] [beam] [wink] [sad] [cool] [innocent] [rolleyes] [whistling] [lol] [huh] [tongue] [love] [sleeping] [yawn] [unsure] [angry] [blink] [crying] [ohmy] [scared] [sleep] [sneaky] [tongue_smile] [thumbdown] [thumbup] [censored] [happybirthday] [ban] [spam] [offtopic] [batman] [ninja] [pirate] [alien] Comment Text Cancel Post comment × Report Cancel Report Abuse × Watch this discussion. 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